Main Article Content
Abstract
This case report highlights a traumatic ulcer mimicking oral squamous cell carcinoma. Oral ulcers, commonly caused by trauma, often present diagnostic challenges. Two male patients, aged 25 and 90, reported painful solitary lingual ulcers resembling malignancy. A biopsy was performed, leading to significant regression and complete healing. Initially misdiagnosed as squamous cell carcinoma, the ulcers required careful clinical evaluation, medical history review, and additional investigations for accurate diagnosis. Histopathology confirmed the diagnosis, emphasizing biopsy’s role in both diagnosis and healing. This report highlights the importance of biopsy in distinguishing traumatic ulcers from malignancy and facilitating proper management.
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References
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- Ishaquddin S, Maya D, Ghadage M. Traumatic ulcer or squamous cell carcinoma of the tongue? Case report. Int J Healthc Biomed Res. 2013;2:57-60.
- Rai V, Mallick R, Kumar R, Jain A, Satpute P. Prevalence of traumatic ulcerative lesions of the oral mucosa: a study in a teaching hospital in northern India. J Family Med Prim Care. 2014;3(3):207-10.
- Kolokythas A, Schwartz S, Douglass G, et al. Oral traumatic ulcers: clinical and histopathologic analysis of 158 cases. J Oral Maxillofac Surg. 2016;74(5):926-32.
- Holmes RG, Chan DC, Singh BB. Chemical burn of the buccal mucosa. Am J Dent. 2004;17:219-20.
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- Scully C, Bagan JV. Adverse drug reactions in the orofacial region. Crit Rev Oral Biol Med. 2004;15:221-39 https://doi.org/10.1177/154411130401500405 .
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- Gándara JM, Diniz M, Gándara P, et al. Lesionesinducidaspor la aplicacióntópica de cocaína. Med Oral. 2002;7:103-7.
- Bascones A, Figuero E, Esparza GC. Úlcerasorales. Med Clin (Barc). 2005;125:590-7 https://doi.org/10.1157/13080655 .
- Jurema ME, Silva DP, Mendes R, et al. Differential diagnosis of single or multiple oral ulcerations. J Oral Maxillofac Res. 2019;10(3).
- Nidarsh H, Mithra H, Aastha P, Raksha B. Differential diagnosis of long-term tongue ulcers. Int Res J Pharm. 2012;3(8):145-8.
- Anura A. Traumatic oral mucosal lesions: a mini review and clinical update. Oral Health Dent Manag. 2014;13(2):254-9.
- Agha RA, Borrelli MR, Farwana R, et al. The SCARE 2020 guideline: updating consensus Surgical CAseREport (SCARE) guidelines. Int J Surg. 2020;84:226-30 https://doi.org/10.1016/j.ijsu.2020.10.034 .
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- Van Heerden WFP, Andre WV. Surgical pathology of oral cancer. DiagnHistopathol. 2009;15(6):296-302 https://doi.org/10.1016/j.mpdhp.2017.04.009.
- Bascones A, Figuero E, Esparza GC. Úlcerasorales. Med Clin (Barc). 2005;125:590-7 https://doi.org/10.1157/13080655 .
- Fitzpatrick SG, Cohen DM, Clark AN. Ulcerated lesions of the oral mucosa: clinical and histologic review. Head Neck Pathol. 2019;13:91-102 https://doi.org/10.1007/s12105-018-0981-8.
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References
Lazos JP, Piemonte ED, Lanfranchi HE, Brunotto MN. Characterization of chronic mechanical irritation in oral cancer. Int J Dent. 2017;2017:1-7
Ishaquddin S, Maya D, Ghadage M. Traumatic ulcer or squamous cell carcinoma of the tongue? Case report. Int J Healthc Biomed Res. 2013;2:57-60.
Rai V, Mallick R, Kumar R, Jain A, Satpute P. Prevalence of traumatic ulcerative lesions of the oral mucosa: a study in a teaching hospital in northern India. J Family Med Prim Care. 2014;3(3):207-10.
Kolokythas A, Schwartz S, Douglass G, et al. Oral traumatic ulcers: clinical and histopathologic analysis of 158 cases. J Oral Maxillofac Surg. 2016;74(5):926-32.
Holmes RG, Chan DC, Singh BB. Chemical burn of the buccal mucosa. Am J Dent. 2004;17:219-20.
Field EA, Allan RB. Review article: oral ulceration – aetiopathogenesis, clinical diagnosis and management in the gastrointestinal clinic. Aliment PharmacolTher. 2003;18:949-62 https://doi.org/10.1046/j.1365-2036.2003.01782.x .
Scully C, Bagan JV. Adverse drug reactions in the orofacial region. Crit Rev Oral Biol Med. 2004;15:221-39 https://doi.org/10.1177/154411130401500405 .
Gonzalez-Moles MA, Bagan-Sebastian JV. Alendronate-related oral mucosa ulcerations. J Oral Pathol Med. 2000;29:514-8 https://doi.org/10.1034/j.1600-0714.2000.291006.x.
Gándara JM, Diniz M, Gándara P, et al. Lesionesinducidaspor la aplicacióntópica de cocaína. Med Oral. 2002;7:103-7.
Bascones A, Figuero E, Esparza GC. Úlcerasorales. Med Clin (Barc). 2005;125:590-7 https://doi.org/10.1157/13080655 .
Jurema ME, Silva DP, Mendes R, et al. Differential diagnosis of single or multiple oral ulcerations. J Oral Maxillofac Res. 2019;10(3).
Nidarsh H, Mithra H, Aastha P, Raksha B. Differential diagnosis of long-term tongue ulcers. Int Res J Pharm. 2012;3(8):145-8.
Anura A. Traumatic oral mucosal lesions: a mini review and clinical update. Oral Health Dent Manag. 2014;13(2):254-9.
Agha RA, Borrelli MR, Farwana R, et al. The SCARE 2020 guideline: updating consensus Surgical CAseREport (SCARE) guidelines. Int J Surg. 2020;84:226-30 https://doi.org/10.1016/j.ijsu.2020.10.034 .
Jensen A, Nolet PS, Diwan MA. Oral squamous cell carcinoma: an atypical presentation mimicking temporomandibular joint disorder. J Can Chiropr Assoc. 2004;48(4):266-72 https://pmc.ncbi.nlm.nih.gov/articles/PMC1769296/.
Van Heerden WFP, Andre WV. Surgical pathology of oral cancer. DiagnHistopathol. 2009;15(6):296-302 https://doi.org/10.1016/j.mpdhp.2017.04.009.
Bascones A, Figuero E, Esparza GC. Úlcerasorales. Med Clin (Barc). 2005;125:590-7 https://doi.org/10.1157/13080655 .
Fitzpatrick SG, Cohen DM, Clark AN. Ulcerated lesions of the oral mucosa: clinical and histologic review. Head Neck Pathol. 2019;13:91-102 https://doi.org/10.1007/s12105-018-0981-8.
Mortazavi H, Safi Y, Baharvand M, Rahmani S. Diagnostic features of common oral ulcerative lesions: an updated decision tree. Int J Dent. 2016;2016:1-14 https://doi.org/10.1155/2016/7278925.